Effects of a natural multi-component compound formulation on the growth, morphology and extracellular matrix production of human adult dermal fibroblasts
Identifieur interne : 000854 ( Main/Exploration ); précédent : 000853; suivant : 000855Effects of a natural multi-component compound formulation on the growth, morphology and extracellular matrix production of human adult dermal fibroblasts
Auteurs : Monica Benvenuto [Italie] ; Rosanna Mattera [Italie] ; Martino Tony Miele [Italie] ; Maria Gabriella Giganti [Italie] ; Ilaria Tresoldi [Italie] ; Loredana Albonici [Italie] ; Vittorio Manzari [Italie] ; Andrea Modesti [Italie] ; Laura Masuelli [Italie] ; Roberto Bei [Italie]Source :
- Experimental and Therapeutic Medicine [ 1792-0981 ] ; 2019.
Abstract
The extracellular matrix (ECM) creates a tissue microenvironment able to regulate cellular signaling. The loss of ECM plasticity is associated with several pathologies, especially those involving chronic inflammation, therefore, the ECM represents a potential therapeutic target for certain conditions. The present study investigated the effects of a natural multi-component compound formulation, Galium-Heel®, on the growth, morphology and ECM production of human dermal fibroblasts (HDF). The effects of the formulation on HDF growth and morphology were assessed by sulforhodamine B assay, trypan blue exclusion staining, FACS and ultrastructural analyses. The effect of the compound on reactive oxygen species production by HDF was performed by dichlorofluorescin diacetate assay. The expression of ECM components, matrix metalloproteinases (MMPs) and signaling molecules was analyzed by western blot analysis. The present results demonstrated that Galium-Heel® did not significantly affect HDF growth, survival, cell cycle or morphology indicating the biocompatibility of the formulation. The formulation demonstrated antioxidant activity. Galium-Heel® was able to modulate ECM by regulating collagens (type I and III) and MMPs-3 and −7 expression. In addition, the formulation was able to regulate molecules involved in TGF-β signalling, including mitogen activated kinase-like protein, GLI family zinc finger 2 and pro-survival proteins such as AKT. The present results demonstrating the effects of a natural multi-component compound on ECM composition, highlighted the possibility of pharmacologically modulating ECM molecules. The recovery and the maintenance of ECM homeostasis might be considered as a potential therapeutic goal to ameliorate pathological conditions.
Url:
DOI: 10.3892/etm.2019.7872
PubMed: 31572512
PubMed Central: 6755435
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000517
- to stream Pmc, to step Curation: 000517
- to stream Pmc, to step Checkpoint: 000795
- to stream Ncbi, to step Merge: 000A69
- to stream Ncbi, to step Curation: 000A69
- to stream Ncbi, to step Checkpoint: 000A69
- to stream Main, to step Merge: 000854
- to stream Main, to step Curation: 000854
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effects of a natural multi-component compound formulation on the growth, morphology and extracellular matrix production of human adult dermal fibroblasts</title><author><name sortKey="Benvenuto, Monica" sort="Benvenuto, Monica" uniqKey="Benvenuto M" first="Monica" last="Benvenuto">Monica Benvenuto</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Mattera, Rosanna" sort="Mattera, Rosanna" uniqKey="Mattera R" first="Rosanna" last="Mattera">Rosanna Mattera</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Miele, Martino Tony" sort="Miele, Martino Tony" uniqKey="Miele M" first="Martino Tony" last="Miele">Martino Tony Miele</name><affiliation wicri:level="1"><nlm:aff id="af2-etm-0-0-7872">Department of Experimental Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Giganti, Maria Gabriella" sort="Giganti, Maria Gabriella" uniqKey="Giganti M" first="Maria Gabriella" last="Giganti">Maria Gabriella Giganti</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Tresoldi, Ilaria" sort="Tresoldi, Ilaria" uniqKey="Tresoldi I" first="Ilaria" last="Tresoldi">Ilaria Tresoldi</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Albonici, Loredana" sort="Albonici, Loredana" uniqKey="Albonici L" first="Loredana" last="Albonici">Loredana Albonici</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Manzari, Vittorio" sort="Manzari, Vittorio" uniqKey="Manzari V" first="Vittorio" last="Manzari">Vittorio Manzari</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Modesti, Andrea" sort="Modesti, Andrea" uniqKey="Modesti A" first="Andrea" last="Modesti">Andrea Modesti</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Masuelli, Laura" sort="Masuelli, Laura" uniqKey="Masuelli L" first="Laura" last="Masuelli">Laura Masuelli</name><affiliation wicri:level="1"><nlm:aff id="af3-etm-0-0-7872">Department of Experimental Medicine, University of Rome ‘Sapienza’, I-00161 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Medicine, University of Rome ‘Sapienza’, I-00161 Rome</wicri:regionArea><wicri:noRegion>I-00161 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Bei, Roberto" sort="Bei, Roberto" uniqKey="Bei R" first="Roberto" last="Bei">Roberto Bei</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31572512</idno><idno type="pmc">6755435</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755435</idno><idno type="RBID">PMC:6755435</idno><idno type="doi">10.3892/etm.2019.7872</idno><date when="2019">2019</date><idno type="wicri:Area/Pmc/Corpus">000517</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000517</idno><idno type="wicri:Area/Pmc/Curation">000517</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000517</idno><idno type="wicri:Area/Pmc/Checkpoint">000795</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000795</idno><idno type="wicri:Area/Ncbi/Merge">000A69</idno><idno type="wicri:Area/Ncbi/Curation">000A69</idno><idno type="wicri:Area/Ncbi/Checkpoint">000A69</idno><idno type="wicri:doubleKey">1792-0981:2019:Benvenuto M:effects:of:a</idno><idno type="wicri:Area/Main/Merge">000854</idno><idno type="wicri:Area/Main/Curation">000854</idno><idno type="wicri:Area/Main/Exploration">000854</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Effects of a natural multi-component compound formulation on the growth, morphology and extracellular matrix production of human adult dermal fibroblasts</title><author><name sortKey="Benvenuto, Monica" sort="Benvenuto, Monica" uniqKey="Benvenuto M" first="Monica" last="Benvenuto">Monica Benvenuto</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Mattera, Rosanna" sort="Mattera, Rosanna" uniqKey="Mattera R" first="Rosanna" last="Mattera">Rosanna Mattera</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Miele, Martino Tony" sort="Miele, Martino Tony" uniqKey="Miele M" first="Martino Tony" last="Miele">Martino Tony Miele</name><affiliation wicri:level="1"><nlm:aff id="af2-etm-0-0-7872">Department of Experimental Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Giganti, Maria Gabriella" sort="Giganti, Maria Gabriella" uniqKey="Giganti M" first="Maria Gabriella" last="Giganti">Maria Gabriella Giganti</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Tresoldi, Ilaria" sort="Tresoldi, Ilaria" uniqKey="Tresoldi I" first="Ilaria" last="Tresoldi">Ilaria Tresoldi</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Albonici, Loredana" sort="Albonici, Loredana" uniqKey="Albonici L" first="Loredana" last="Albonici">Loredana Albonici</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Manzari, Vittorio" sort="Manzari, Vittorio" uniqKey="Manzari V" first="Vittorio" last="Manzari">Vittorio Manzari</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Modesti, Andrea" sort="Modesti, Andrea" uniqKey="Modesti A" first="Andrea" last="Modesti">Andrea Modesti</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Masuelli, Laura" sort="Masuelli, Laura" uniqKey="Masuelli L" first="Laura" last="Masuelli">Laura Masuelli</name><affiliation wicri:level="1"><nlm:aff id="af3-etm-0-0-7872">Department of Experimental Medicine, University of Rome ‘Sapienza’, I-00161 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Medicine, University of Rome ‘Sapienza’, I-00161 Rome</wicri:regionArea><wicri:noRegion>I-00161 Rome</wicri:noRegion></affiliation></author><author><name sortKey="Bei, Roberto" sort="Bei, Roberto" uniqKey="Bei R" first="Roberto" last="Bei">Roberto Bei</name><affiliation wicri:level="1"><nlm:aff id="af1-etm-0-0-7872">Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Translational Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome</wicri:regionArea><wicri:noRegion>I-00133 Rome</wicri:noRegion></affiliation></author></analytic><series><title level="j">Experimental and Therapeutic Medicine</title><idno type="ISSN">1792-0981</idno><idno type="eISSN">1792-1015</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The extracellular matrix (ECM) creates a tissue microenvironment able to regulate cellular signaling. The loss of ECM plasticity is associated with several pathologies, especially those involving chronic inflammation, therefore, the ECM represents a potential therapeutic target for certain conditions. The present study investigated the effects of a natural multi-component compound formulation, Galium-Heel<sup>®</sup>, on the growth, morphology and ECM production of human dermal fibroblasts (HDF). The effects of the formulation on HDF growth and morphology were assessed by sulforhodamine B assay, trypan blue exclusion staining, FACS and ultrastructural analyses. The effect of the compound on reactive oxygen species production by HDF was performed by dichlorofluorescin diacetate assay. The expression of ECM components, matrix metalloproteinases (MMPs) and signaling molecules was analyzed by western blot analysis. The present results demonstrated that Galium-Heel<sup>®</sup> did not significantly affect HDF growth, survival, cell cycle or morphology indicating the biocompatibility of the formulation. The formulation demonstrated antioxidant activity. Galium-Heel<sup>®</sup> was able to modulate ECM by regulating collagens (type I and III) and MMPs-3 and −7 expression. In addition, the formulation was able to regulate molecules involved in TGF-β signalling, including mitogen activated kinase-like protein, GLI family zinc finger 2 and pro-survival proteins such as AKT. The present results demonstrating the effects of a natural multi-component compound on ECM composition, highlighted the possibility of pharmacologically modulating ECM molecules. The recovery and the maintenance of ECM homeostasis might be considered as a potential therapeutic goal to ameliorate pathological conditions.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Nystrom, A" uniqKey="Nystrom A">A Nyström</name></author><author><name sortKey="Bruckner Tuderman, L" uniqKey="Bruckner Tuderman L">L Bruckner-Tuderman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bei, R" uniqKey="Bei R">R Bei</name></author><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Palumbo, C" uniqKey="Palumbo C">C Palumbo</name></author><author><name sortKey="Tresoldi, I" uniqKey="Tresoldi I">I Tresoldi</name></author><author><name sortKey="Scardino, A" uniqKey="Scardino A">A Scardino</name></author><author><name sortKey="Modesti, A" uniqKey="Modesti A">A Modesti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iozzo, Rv" uniqKey="Iozzo R">RV Iozzo</name></author><author><name sortKey="Gubbiotti, Ma" uniqKey="Gubbiotti M">MA Gubbiotti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Walker, C" uniqKey="Walker C">C Walker</name></author><author><name sortKey="Mojares, E" uniqKey="Mojares E">E Mojares</name></author><author><name sortKey="Del Rio Hernandez, A" uniqKey="Del Rio Hernandez A">A Del Río Hernández</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, L" uniqKey="Li L">L Li</name></author><author><name sortKey="Zhao, Q" uniqKey="Zhao Q">Q Zhao</name></author><author><name sortKey="Kong, W" uniqKey="Kong W">W Kong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Minihane, Am" uniqKey="Minihane A">AM Minihane</name></author><author><name sortKey="Vinoy, S" uniqKey="Vinoy S">S Vinoy</name></author><author><name sortKey="Russell, Wr" uniqKey="Russell W">WR Russell</name></author><author><name sortKey="Baka, A" uniqKey="Baka A">A Baka</name></author><author><name sortKey="Roche, Hm" uniqKey="Roche H">HM Roche</name></author><author><name sortKey="Tuohy, Km" uniqKey="Tuohy K">KM Tuohy</name></author><author><name sortKey="Teeling, Jl" uniqKey="Teeling J">JL Teeling</name></author><author><name sortKey="Blaak, Ee" uniqKey="Blaak E">EE Blaak</name></author><author><name sortKey="Fenech, M" uniqKey="Fenech M">M Fenech</name></author><author><name sortKey="Vauzour, D" uniqKey="Vauzour D">D Vauzour</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Theocharis, Ad" uniqKey="Theocharis A">AD Theocharis</name></author><author><name sortKey="Skandalis, Ss" uniqKey="Skandalis S">SS Skandalis</name></author><author><name sortKey="Gialeli, C" uniqKey="Gialeli C">C Gialeli</name></author><author><name sortKey="Karamanos, Nk" uniqKey="Karamanos N">NK Karamanos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Soylemezoglu, O" uniqKey="Soylemezoglu O">O Soylemezoglu</name></author><author><name sortKey="Wild, G" uniqKey="Wild G">G Wild</name></author><author><name sortKey="Dalley, Aj" uniqKey="Dalley A">AJ Dalley</name></author><author><name sortKey="Macneil, S" uniqKey="Macneil S">S MacNeil</name></author><author><name sortKey="Milford Ward, A" uniqKey="Milford Ward A">A Milford-Ward</name></author><author><name sortKey="Brown, Cb" uniqKey="Brown C">CB Brown</name></author><author><name sortKey="El Nahas, Am" uniqKey="El Nahas A">AM el Nahas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arpino, V" uniqKey="Arpino V">V Arpino</name></author><author><name sortKey="Brock, M" uniqKey="Brock M">M Brock</name></author><author><name sortKey="Gill, Se" uniqKey="Gill S">SE Gill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Randelli, F" uniqKey="Randelli F">F Randelli</name></author><author><name sortKey="Menon, A" uniqKey="Menon A">A Menon</name></author><author><name sortKey="Giai Via, A" uniqKey="Giai Via A">A Giai Via</name></author><author><name sortKey="Mazzoleni, Mg" uniqKey="Mazzoleni M">MG Mazzoleni</name></author><author><name sortKey="Sciancalepore, F" uniqKey="Sciancalepore F">F Sciancalepore</name></author><author><name sortKey="Brioschi, M" uniqKey="Brioschi M">M Brioschi</name></author><author><name sortKey="Gagliano, N" uniqKey="Gagliano N">N Gagliano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Karsdal, Ma" uniqKey="Karsdal M">MA Karsdal</name></author><author><name sortKey="Nielsen, Mj" uniqKey="Nielsen M">MJ Nielsen</name></author><author><name sortKey="Sand, Jm" uniqKey="Sand J">JM Sand</name></author><author><name sortKey="Henriksen, K" uniqKey="Henriksen K">K Henriksen</name></author><author><name sortKey="Genovese, F" uniqKey="Genovese F">F Genovese</name></author><author><name sortKey="Bay Jensen, Ac" uniqKey="Bay Jensen A">AC Bay-Jensen</name></author><author><name sortKey="Smith, V" uniqKey="Smith V">V Smith</name></author><author><name sortKey="Adamkewicz, Ji" uniqKey="Adamkewicz J">JI Adamkewicz</name></author><author><name sortKey="Christiansen, C" uniqKey="Christiansen C">C Christiansen</name></author><author><name sortKey="Leeming, Dj" uniqKey="Leeming D">DJ Leeming</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barascuk, N" uniqKey="Barascuk N">N Barascuk</name></author><author><name sortKey="Vassiliadis, E" uniqKey="Vassiliadis E">E Vassiliadis</name></author><author><name sortKey="Larsen, L" uniqKey="Larsen L">L Larsen</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J Wang</name></author><author><name sortKey="Zheng, Q" uniqKey="Zheng Q">Q Zheng</name></author><author><name sortKey="Xing, R" uniqKey="Xing R">R Xing</name></author><author><name sortKey="Cao, Y" uniqKey="Cao Y">Y Cao</name></author><author><name sortKey="Crespo, C" uniqKey="Crespo C">C Crespo</name></author><author><name sortKey="Lapret, I" uniqKey="Lapret I">I Lapret</name></author><author><name sortKey="Sabatini, M" uniqKey="Sabatini M">M Sabatini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liang, Z" uniqKey="Liang Z">Z Liang</name></author><author><name sortKey="Li, T" uniqKey="Li T">T Li</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name></author><author><name sortKey="Xu, J" uniqKey="Xu J">J Xu</name></author><author><name sortKey="Di, W" uniqKey="Di W">W Di</name></author><author><name sortKey="Yang, Z" uniqKey="Yang Z">Z Yang</name></author><author><name sortKey="Hu, W" uniqKey="Hu W">W Hu</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, N" uniqKey="Zhang N">N Zhang</name></author><author><name sortKey="Wei, Wy" uniqKey="Wei W">WY Wei</name></author><author><name sortKey="Li, Ll" uniqKey="Li L">LL Li</name></author><author><name sortKey="Hu, C" uniqKey="Hu C">C Hu</name></author><author><name sortKey="Tang, Qz" uniqKey="Tang Q">QZ Tang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Katoh, M" uniqKey="Katoh M">M Katoh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reale, Fr" uniqKey="Reale F">FR Reale</name></author><author><name sortKey="Griyn, Tw" uniqKey="Griyn T">TW GriYn</name></author><author><name sortKey="Compton, Jm" uniqKey="Compton J">JM Compton</name></author><author><name sortKey="Graham, S" uniqKey="Graham S">S Graham</name></author><author><name sortKey="Townes, Pl" uniqKey="Townes P">PL Townes</name></author><author><name sortKey="Bogden, A" uniqKey="Bogden A">A Bogden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Benvenuto, M" uniqKey="Benvenuto M">M Benvenuto</name></author><author><name sortKey="Mattera, R" uniqKey="Mattera R">R Mattera</name></author><author><name sortKey="Di Stefano, E" uniqKey="Di Stefano E">E Di Stefano</name></author><author><name sortKey="Zago, E" uniqKey="Zago E">E Zago</name></author><author><name sortKey="Taffera, G" uniqKey="Taffera G">G Taffera</name></author><author><name sortKey="Tresoldi, I" uniqKey="Tresoldi I">I Tresoldi</name></author><author><name sortKey="Giganti, Mg" uniqKey="Giganti M">MG Giganti</name></author><author><name sortKey="Frajese, Gv" uniqKey="Frajese G">GV Frajese</name></author><author><name sortKey="Berardi, G" uniqKey="Berardi G">G Berardi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Strober, W" uniqKey="Strober W">W Strober</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benvenuto, M" uniqKey="Benvenuto M">M Benvenuto</name></author><author><name sortKey="Mattera, R" uniqKey="Mattera R">R Mattera</name></author><author><name sortKey="Sticca, Ji" uniqKey="Sticca J">JI Sticca</name></author><author><name sortKey="Rossi, P" uniqKey="Rossi P">P Rossi</name></author><author><name sortKey="Cipriani, C" uniqKey="Cipriani C">C Cipriani</name></author><author><name sortKey="Giganti, Mg" uniqKey="Giganti M">MG Giganti</name></author><author><name sortKey="Volpi, A" uniqKey="Volpi A">A Volpi</name></author><author><name sortKey="Modesti, A" uniqKey="Modesti A">A Modesti</name></author><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Bei, R" uniqKey="Bei R">R Bei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Pantanella, F" uniqKey="Pantanella F">F Pantanella</name></author><author><name sortKey="La Regina, G" uniqKey="La Regina G">G La Regina</name></author><author><name sortKey="Benvenuto, M" uniqKey="Benvenuto M">M Benvenuto</name></author><author><name sortKey="Fantini, M" uniqKey="Fantini M">M Fantini</name></author><author><name sortKey="Mattera, R" uniqKey="Mattera R">R Mattera</name></author><author><name sortKey="Di Stefano, E" uniqKey="Di Stefano E">E Di Stefano</name></author><author><name sortKey="Mattei, M" uniqKey="Mattei M">M Mattei</name></author><author><name sortKey="Silvestri, R" uniqKey="Silvestri R">R Silvestri</name></author><author><name sortKey="Schippa, S" uniqKey="Schippa S">S Schippa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benvenuto, M" uniqKey="Benvenuto M">M Benvenuto</name></author><author><name sortKey="Mattera, R" uniqKey="Mattera R">R Mattera</name></author><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Taffera, G" uniqKey="Taffera G">G Taffera</name></author><author><name sortKey="Andracchio, O" uniqKey="Andracchio O">O Andracchio</name></author><author><name sortKey="Tresoldi, I" uniqKey="Tresoldi I">I Tresoldi</name></author><author><name sortKey="Lido, P" uniqKey="Lido P">P Lido</name></author><author><name sortKey="Giganti, Mg" uniqKey="Giganti M">MG Giganti</name></author><author><name sortKey="Godos, J" uniqKey="Godos J">J Godos</name></author><author><name sortKey="Modesti, A" uniqKey="Modesti A">A Modesti</name></author><author><name sortKey="Bei, R" uniqKey="Bei R">R Bei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Benvenuto, M" uniqKey="Benvenuto M">M Benvenuto</name></author><author><name sortKey="Di Stefano, E" uniqKey="Di Stefano E">E Di Stefano</name></author><author><name sortKey="Mattera, R" uniqKey="Mattera R">R Mattera</name></author><author><name sortKey="Fantini, M" uniqKey="Fantini M">M Fantini</name></author><author><name sortKey="De Feudis, G" uniqKey="De Feudis G">G De Feudis</name></author><author><name sortKey="De Smaele, E" uniqKey="De Smaele E">E De Smaele</name></author><author><name sortKey="Tresoldi, I" uniqKey="Tresoldi I">I Tresoldi</name></author><author><name sortKey="Giganti, Mg" uniqKey="Giganti M">MG Giganti</name></author><author><name sortKey="Modesti, A" uniqKey="Modesti A">A Modesti</name></author><author><name sortKey="Bei, R" uniqKey="Bei R">R Bei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Granato, M" uniqKey="Granato M">M Granato</name></author><author><name sortKey="Benvenuto, M" uniqKey="Benvenuto M">M Benvenuto</name></author><author><name sortKey="Mattera, R" uniqKey="Mattera R">R Mattera</name></author><author><name sortKey="Bernardini, R" uniqKey="Bernardini R">R Bernardini</name></author><author><name sortKey="Mattei, M" uniqKey="Mattei M">M Mattei</name></author><author><name sortKey="D Amati, G" uniqKey="D Amati G">G d'Amati</name></author><author><name sortKey="D Orazi, G" uniqKey="D Orazi G">G D'Orazi</name></author><author><name sortKey="Faggioni, A" uniqKey="Faggioni A">A Faggioni</name></author><author><name sortKey="Bei, R" uniqKey="Bei R">R Bei</name></author><author><name sortKey="Cirone, M" uniqKey="Cirone M">M Cirone</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Angelucci, C" uniqKey="Angelucci C">C Angelucci</name></author><author><name sortKey="D Alessio, A" uniqKey="D Alessio A">A D'Alessio</name></author><author><name sortKey="Lama, G" uniqKey="Lama G">G Lama</name></author><author><name sortKey="Binda, E" uniqKey="Binda E">E Binda</name></author><author><name sortKey="Mangiola, A" uniqKey="Mangiola A">A Mangiola</name></author><author><name sortKey="Vescovi, Al" uniqKey="Vescovi A">AL Vescovi</name></author><author><name sortKey="Proietti, G" uniqKey="Proietti G">G Proietti</name></author><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Bei, R" uniqKey="Bei R">R Bei</name></author><author><name sortKey="Fazi, B" uniqKey="Fazi B">B Fazi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stankovi, M" uniqKey="Stankovi M">M Stanković</name></author><author><name sortKey="Radojevi, I" uniqKey="Radojevi I">I Radojević</name></author><author><name sortKey=" Ur I, M" uniqKey=" Ur I M">M Ćurčić</name></author><author><name sortKey="Vasi, S" uniqKey="Vasi S">S Vasić</name></author><author><name sortKey="Topuzovi, M" uniqKey="Topuzovi M">M Topuzović</name></author><author><name sortKey=" Omi, L" uniqKey=" Omi L">L Čomić</name></author><author><name sortKey="Markovi, S" uniqKey="Markovi S">S Marković</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sentjurc, M" uniqKey="Sentjurc M">M Sentjurc</name></author><author><name sortKey="Nemec, M" uniqKey="Nemec M">M Nemec</name></author><author><name sortKey="Connor, Hd" uniqKey="Connor H">HD Connor</name></author><author><name sortKey="Abram, V" uniqKey="Abram V">V Abram</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marrassini, C" uniqKey="Marrassini C">C Marrassini</name></author><author><name sortKey="Acevedo, C" uniqKey="Acevedo C">C Acevedo</name></author><author><name sortKey="Mi O, J" uniqKey="Mi O J">J Miño</name></author><author><name sortKey="Ferraro, G" uniqKey="Ferraro G">G Ferraro</name></author><author><name sortKey="Gorzalczany, S" uniqKey="Gorzalczany S">S Gorzalczany</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, P" uniqKey="Lu P">P Lu</name></author><author><name sortKey="Takai, K" uniqKey="Takai K">K Takai</name></author><author><name sortKey="Weaver, Vm" uniqKey="Weaver V">VM Weaver</name></author><author><name sortKey="Werb, Z" uniqKey="Werb Z">Z Werb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sanchavanakit, N" uniqKey="Sanchavanakit N">N Sanchavanakit</name></author><author><name sortKey="Saengtong, W" uniqKey="Saengtong W">W Saengtong</name></author><author><name sortKey="Manokawinchoke, J" uniqKey="Manokawinchoke J">J Manokawinchoke</name></author><author><name sortKey="Pavasant, P" uniqKey="Pavasant P">P Pavasant</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, H" uniqKey="Yang H">H Yang</name></author><author><name sortKey="Gao, F" uniqKey="Gao F">F Gao</name></author><author><name sortKey="Li, X" uniqKey="Li X">X Li</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J Wang</name></author><author><name sortKey="Liu, H" uniqKey="Liu H">H Liu</name></author><author><name sortKey="Zheng, Z" uniqKey="Zheng Z">Z Zheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saed, Gm" uniqKey="Saed G">GM Saed</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W Zhang</name></author><author><name sortKey="Chegini, N" uniqKey="Chegini N">N Chegini</name></author><author><name sortKey="Holmdahl, L" uniqKey="Holmdahl L">L Holmdahl</name></author><author><name sortKey="Diamond, Mp" uniqKey="Diamond M">MP Diamond</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Forel, Jm" uniqKey="Forel J">JM Forel</name></author><author><name sortKey="Guervilly, C" uniqKey="Guervilly C">C Guervilly</name></author><author><name sortKey="Farnarier, C" uniqKey="Farnarier C">C Farnarier</name></author><author><name sortKey="Donati, Sy" uniqKey="Donati S">SY Donati</name></author><author><name sortKey="Hraiech, S" uniqKey="Hraiech S">S Hraiech</name></author><author><name sortKey="Persico, N" uniqKey="Persico N">N Persico</name></author><author><name sortKey="Allardet Servent, J" uniqKey="Allardet Servent J">J Allardet-Servent</name></author><author><name sortKey="Coiffard, B" uniqKey="Coiffard B">B Coiffard</name></author><author><name sortKey="Gainnier, M" uniqKey="Gainnier M">M Gainnier</name></author><author><name sortKey="Loundou, A" uniqKey="Loundou A">A Loundou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rojkind, M" uniqKey="Rojkind M">M Rojkind</name></author><author><name sortKey="Giambrone, Ma" uniqKey="Giambrone M">MA Giambrone</name></author><author><name sortKey="Biempica, L" uniqKey="Biempica L">L Biempica</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Javelaud, D" uniqKey="Javelaud D">D Javelaud</name></author><author><name sortKey="Pierrat, Mj" uniqKey="Pierrat M">MJ Pierrat</name></author><author><name sortKey="Mauviel, A" uniqKey="Mauviel A">A Mauviel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liang, R" uniqKey="Liang R">R Liang</name></author><author><name sortKey="Sumova, B" uniqKey="Sumova B">B Šumová</name></author><author><name sortKey="Cordazzo, C" uniqKey="Cordazzo C">C Cordazzo</name></author><author><name sortKey="Mallano, T" uniqKey="Mallano T">T Mallano</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Wohlfahrt, T" uniqKey="Wohlfahrt T">T Wohlfahrt</name></author><author><name sortKey="Dees, C" uniqKey="Dees C">C Dees</name></author><author><name sortKey="Ramming, A" uniqKey="Ramming A">A Ramming</name></author><author><name sortKey="Krasowska, D" uniqKey="Krasowska D">D Krasowska</name></author><author><name sortKey="Michalska Jakubus, M" uniqKey="Michalska Jakubus M">M Michalska-Jakubus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moncada, S" uniqKey="Moncada S">S Moncada</name></author><author><name sortKey="Higgs, A" uniqKey="Higgs A">A Higgs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xia, W" uniqKey="Xia W">W Xia</name></author><author><name sortKey="Szomor, Z" uniqKey="Szomor Z">Z Szomor</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Murrell, Ga" uniqKey="Murrell G">GA Murrell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lundberg, Jo" uniqKey="Lundberg J">JO Lundberg</name></author><author><name sortKey="Weitzberg, E" uniqKey="Weitzberg E">E Weitzberg</name></author><author><name sortKey="Gladwin, Mt" uniqKey="Gladwin M">MT Gladwin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gilkes, Dm" uniqKey="Gilkes D">DM Gilkes</name></author><author><name sortKey="Semenza, Gl" uniqKey="Semenza G">GL Semenza</name></author><author><name sortKey="Wirtz, D" uniqKey="Wirtz D">D Wirtz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Negahdary, M" uniqKey="Negahdary M">M Negahdary</name></author><author><name sortKey="Chelongar, R" uniqKey="Chelongar R">R Chelongar</name></author><author><name sortKey="Zadeh, Sk" uniqKey="Zadeh S">SK Zadeh</name></author><author><name sortKey="Ajdary, M" uniqKey="Ajdary M">M Ajdary</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hashimoto, M" uniqKey="Hashimoto M">M Hashimoto</name></author><author><name sortKey="Sasaki, Ji" uniqKey="Sasaki J">JI Sasaki</name></author><author><name sortKey="Yamaguchi, S" uniqKey="Yamaguchi S">S Yamaguchi</name></author><author><name sortKey="Kawai, K" uniqKey="Kawai K">K Kawai</name></author><author><name sortKey="Kawakami, H" uniqKey="Kawakami H">H Kawakami</name></author><author><name sortKey="Iwasaki, Y" uniqKey="Iwasaki Y">Y Iwasaki</name></author><author><name sortKey="Imazato, S" uniqKey="Imazato S">S Imazato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Veerendhar, A" uniqKey="Veerendhar A">A Veerendhar</name></author><author><name sortKey="Reich, R" uniqKey="Reich R">R Reich</name></author><author><name sortKey="Breuer, E" uniqKey="Breuer E">E Breuer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Slompo, C" uniqKey="Slompo C">C Slompo</name></author><author><name sortKey="Buzalaf, Cp" uniqKey="Buzalaf C">CP Buzalaf</name></author><author><name sortKey="Damante, Ca" uniqKey="Damante C">CA Damante</name></author><author><name sortKey="Martins, Gm" uniqKey="Martins G">GM Martins</name></author><author><name sortKey="Hannas, Ar" uniqKey="Hannas A">AR Hannas</name></author><author><name sortKey="Buzalaf, Ma" uniqKey="Buzalaf M">MA Buzalaf</name></author><author><name sortKey="Oliveira, Rc" uniqKey="Oliveira R">RC Oliveira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suszko, A" uniqKey="Suszko A">A Suszko</name></author><author><name sortKey="Obmi Ska Mrukowicz, B" uniqKey="Obmi Ska Mrukowicz B">B Obmińska-Mrukowicz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Han, X" uniqKey="Han X">X Han</name></author><author><name sortKey="Parker, Tl" uniqKey="Parker T">TL Parker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rastogi, S" uniqKey="Rastogi S">S Rastogi</name></author><author><name sortKey="Pandey, Mm" uniqKey="Pandey M">MM Pandey</name></author><author><name sortKey="Kumar Singh Rawat, A" uniqKey="Kumar Singh Rawat A">A Kumar Singh Rawat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ra, Hj" uniqKey="Ra H">HJ Ra</name></author><author><name sortKey="Lee, Hj" uniqKey="Lee H">HJ Lee</name></author><author><name sortKey="Jo, Hs" uniqKey="Jo H">HS Jo</name></author><author><name sortKey="Nam, Dc" uniqKey="Nam D">DC Nam</name></author><author><name sortKey="Lee, Yb" uniqKey="Lee Y">YB Lee</name></author><author><name sortKey="Kang, Bh" uniqKey="Kang B">BH Kang</name></author><author><name sortKey="Moon, Dk" uniqKey="Moon D">DK Moon</name></author><author><name sortKey="Kim, Dh" uniqKey="Kim D">DH Kim</name></author><author><name sortKey="Lee, Cj" uniqKey="Lee C">CJ Lee</name></author><author><name sortKey="Hwang, Sc" uniqKey="Hwang S">SC Hwang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silacci, P" uniqKey="Silacci P">P Silacci</name></author><author><name sortKey="Dayer, Jm" uniqKey="Dayer J">JM Dayer</name></author><author><name sortKey="Desgeorges, A" uniqKey="Desgeorges A">A Desgeorges</name></author><author><name sortKey="Peter, R" uniqKey="Peter R">R Peter</name></author><author><name sortKey="Manueddu, C" uniqKey="Manueddu C">C Manueddu</name></author><author><name sortKey="Guerne, Pa" uniqKey="Guerne P">PA Guerne</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Offergeld, R" uniqKey="Offergeld R">R Offergeld</name></author><author><name sortKey="Reinecker, C" uniqKey="Reinecker C">C Reinecker</name></author><author><name sortKey="Gumz, E" uniqKey="Gumz E">E Gumz</name></author><author><name sortKey="Schrum, S" uniqKey="Schrum S">S Schrum</name></author><author><name sortKey="Treiber, R" uniqKey="Treiber R">R Treiber</name></author><author><name sortKey="Neth, Rd" uniqKey="Neth R">RD Neth</name></author><author><name sortKey="Gohla, Sh" uniqKey="Gohla S">SH Gohla</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sunila, Es" uniqKey="Sunila E">ES Sunila</name></author><author><name sortKey="Hamsa, Tp" uniqKey="Hamsa T">TP Hamsa</name></author><author><name sortKey="Kuttan, G" uniqKey="Kuttan G">G Kuttan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Marzocchella, L" uniqKey="Marzocchella L">L Marzocchella</name></author><author><name sortKey="Focaccetti, C" uniqKey="Focaccetti C">C Focaccetti</name></author><author><name sortKey="Tresoldi, I" uniqKey="Tresoldi I">I Tresoldi</name></author><author><name sortKey="Palumbo, C" uniqKey="Palumbo C">C Palumbo</name></author><author><name sortKey="Izzi, V" uniqKey="Izzi V">V Izzi</name></author><author><name sortKey="Benvenuto, M" uniqKey="Benvenuto M">M Benvenuto</name></author><author><name sortKey="Fantini, M" uniqKey="Fantini M">M Fantini</name></author><author><name sortKey="Lista, F" uniqKey="Lista F">F Lista</name></author><author><name sortKey="Tarantino, U" uniqKey="Tarantino U">U Tarantino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Di Stefano, E" uniqKey="Di Stefano E">E Di Stefano</name></author><author><name sortKey="Fantini, M" uniqKey="Fantini M">M Fantini</name></author><author><name sortKey="Mattera, R" uniqKey="Mattera R">R Mattera</name></author><author><name sortKey="Benvenuto, M" uniqKey="Benvenuto M">M Benvenuto</name></author><author><name sortKey="Marzocchella, L" uniqKey="Marzocchella L">L Marzocchella</name></author><author><name sortKey="Sacchetti, P" uniqKey="Sacchetti P">P Sacchetti</name></author><author><name sortKey="Focaccetti, C" uniqKey="Focaccetti C">C Focaccetti</name></author><author><name sortKey="Bernardini, R" uniqKey="Bernardini R">R Bernardini</name></author><author><name sortKey="Tresoldi, I" uniqKey="Tresoldi I">I Tresoldi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fantini, M" uniqKey="Fantini M">M Fantini</name></author><author><name sortKey="Benvenuto, M" uniqKey="Benvenuto M">M Benvenuto</name></author><author><name sortKey="Masuelli, L" uniqKey="Masuelli L">L Masuelli</name></author><author><name sortKey="Frajese, Gv" uniqKey="Frajese G">GV Frajese</name></author><author><name sortKey="Tresoldi, I" uniqKey="Tresoldi I">I Tresoldi</name></author><author><name sortKey="Modesti, A" uniqKey="Modesti A">A Modesti</name></author><author><name sortKey="Bei, R" uniqKey="Bei R">R Bei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rhee, S" uniqKey="Rhee S">S Rhee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Langevin, Hm" uniqKey="Langevin H">HM Langevin</name></author><author><name sortKey="Bouffard, Na" uniqKey="Bouffard N">NA Bouffard</name></author><author><name sortKey="Fox, Jr" uniqKey="Fox J">JR Fox</name></author><author><name sortKey="Palmer, Bm" uniqKey="Palmer B">BM Palmer</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name></author><author><name sortKey="Iatridis, Jc" uniqKey="Iatridis J">JC Iatridis</name></author><author><name sortKey="Barnes, Wd" uniqKey="Barnes W">WD Barnes</name></author><author><name sortKey="Badger, Gj" uniqKey="Badger G">GJ Badger</name></author><author><name sortKey="Howe, Ak" uniqKey="Howe A">AK Howe</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Italie</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Benvenuto, Monica" sort="Benvenuto, Monica" uniqKey="Benvenuto M" first="Monica" last="Benvenuto">Monica Benvenuto</name></noRegion><name sortKey="Albonici, Loredana" sort="Albonici, Loredana" uniqKey="Albonici L" first="Loredana" last="Albonici">Loredana Albonici</name><name sortKey="Bei, Roberto" sort="Bei, Roberto" uniqKey="Bei R" first="Roberto" last="Bei">Roberto Bei</name><name sortKey="Giganti, Maria Gabriella" sort="Giganti, Maria Gabriella" uniqKey="Giganti M" first="Maria Gabriella" last="Giganti">Maria Gabriella Giganti</name><name sortKey="Manzari, Vittorio" sort="Manzari, Vittorio" uniqKey="Manzari V" first="Vittorio" last="Manzari">Vittorio Manzari</name><name sortKey="Masuelli, Laura" sort="Masuelli, Laura" uniqKey="Masuelli L" first="Laura" last="Masuelli">Laura Masuelli</name><name sortKey="Mattera, Rosanna" sort="Mattera, Rosanna" uniqKey="Mattera R" first="Rosanna" last="Mattera">Rosanna Mattera</name><name sortKey="Miele, Martino Tony" sort="Miele, Martino Tony" uniqKey="Miele M" first="Martino Tony" last="Miele">Martino Tony Miele</name><name sortKey="Modesti, Andrea" sort="Modesti, Andrea" uniqKey="Modesti A" first="Andrea" last="Modesti">Andrea Modesti</name><name sortKey="Tresoldi, Ilaria" sort="Tresoldi, Ilaria" uniqKey="Tresoldi I" first="Ilaria" last="Tresoldi">Ilaria Tresoldi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000854 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000854 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:6755435
|texte= Effects of a natural multi-component compound formulation on the growth, morphology and extracellular matrix production of human adult dermal fibroblasts
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31572512" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ChloroquineV1
| This area was generated with Dilib version V0.6.33. |  |